HKU HKU Dept of Statistics & Actuarial Science, HKU

Seminar by Dr. Bianca DUMITRASCU from University of Cambridge

DateMay 26, 2021, Wednesday
Time4:00 p.m. - 5:00 p.m.
Venuevia Zoom
TitleComputational foundations of morphogenomics

Genomic data are available at unprecedented scales due to developments in high throughput sequencing and imaging technologies. In parallel, innovations in statistics and machine learning boast successful algorithms for a wide array of engineering applications. However, bridging these two worlds—the world of real, messy biological data, and that of algorithms and computation—remains challenging. In this talk, I will review recent attempts to extract interpretable representations in genomics and imaging studies. I will discuss pitfalls and formulate open questions with an emphasis on statistical challenges arising from both data collection and data analysis, with the final goal of building a foundation for and testing the limits of computational morphogenomics – the attempt to determine shape, form and trajectory from genomic information.

About the speaker

Dr. Bianca Dumitrascu is currently a Departmental Early Career Fellow in the Accelerate Programme for Scientific Discovery at the Department of Computer Science and Technology in the University of Cambridge and earned a PhD in Quantitative and Computational Biology at Princeton University. Previously, Dr. Dumitrascu was a Member at the School of Mathematics at the Institute for Advanced Study in Princeton, USA and was a post-doctoral researcher in the Department of Statistics at Duke University.